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Pharmacology and Toxicology

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Showing page 3 of 22 pages of list content

  • Discovery and biological evaluation of a potent small molecule CRM1 inhibitor for its selective ablation of extranodal NK/T cell lymphoma

    This article's authors
    1. He Liu
    2. Meishuo Liu
    3. Xibao Tian
    4. Haina Wang
    5. Jiujiao Gao
    6. Hanrui Li
    7. Zhehuan Zhao
    8. Yu Liu
    9. Caigang Liu
    10. Xuan Chen
    11. Yongliang Yang
    This article has 4 evaluations Latest evaluation on Oct 3, 2023 Published on Dec 10, 2022
  • A novel triptolide analog downregulates NF-κB and induces mitochondrial apoptosis pathways in human pancreatic cancer

    This article's authors
    1. Qiaomu Tian
    2. Peng Zhang
    3. Yihan Wang
    4. Youhui Si
    5. Dengping Yin
    6. Christopher R Weber
    7. Melissa L Fishel
    8. Karen E Pollok
    9. Bo Qiu
    10. Fei Xiao
    11. Anita S Chong
    This article has 5 evaluations Latest evaluation on Sep 28, 2023 Published on Feb 15, 2023
  • Death by a Thousand Cuts – Combining Kinase Inhibitors for Selective Target Inhibition and Rational Polypharmacology

    This article's authors
    1. Ian R. Outhwaite
    2. Sukrit Singh
    3. Benedict-Tilman Berger
    4. Stefan Knapp
    5. John D. Chodera
    6. Markus A. Seeliger
    This article has 5 evaluations Latest evaluation on Sep 27, 2023 Published on Jan 16, 2023
  • Optical Control of G-Actin with a Photoswitchable Latrunculin

    This article's authors
    1. Nynke A. Vepřek
    2. Madeline H. Cooper
    3. Laura Laprell
    4. Emily Jie-Ning Yang
    5. Sander Folkerts
    6. Ruiyang Bao
    7. Thomas G. Oertner
    8. Liza A. Pon
    9. J. Bradley Zuchero
    10. Dirk H. Trauner
    This article has 1 evaluations Latest evaluation on Sep 14, 2023 Published on Jul 19, 2023
  • The G protein biased serotonin 5-HT 2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice

    This article's authors
    1. Vladimir M. Pogorelov
    2. Ramona M. Rodriguiz
    3. Bryan L. Roth
    4. William C. Wetsel
    This article has 1 evaluations Latest evaluation on Sep 8, 2023 Published on Jun 5, 2023
  • The herbicide acetochlor causes lipid peroxidation by inhibition of glutathione peroxidase 4

    This article's authors
    1. Fahmi Mesmar
    2. Maram Muhsen
    3. Jason P. Tourigny
    4. Jason M. Tennessen
    5. Maria Bondesson
    This article has 1 evaluations Latest evaluation on Aug 11, 2023 Published on Apr 14, 2023
  • Natural and engineered mediators of desiccation tolerance stabilize Human Blood Clotting Factor VIII in a dry state

    This article's authors
    1. Maxwell H. Packebush
    2. Silvia Sanchez-Martinez
    3. Sourav Biswas
    4. KC Shraddha
    5. Kenny Nguyen
    6. Thomas C. Boothby
    This article has 2 evaluations Latest evaluation on Apr 14, 2023 Published on Nov 29, 2022
  • A generic binding pocket for small moleculeIKsactivators at the extracellular inter-subunit interface of KCNQ1 and KCNE1 channel complexes

    This article's authors
    1. Magnus Chan
    2. Harutyun Sahakyan
    3. Jodene Eldstrom
    4. Daniel Sastre
    5. Yundi Wang
    6. Ying Dou
    7. Marc Pourrier
    8. Vitya Vardanyan
    9. David Fedida
    This article has 10 evaluations Latest evaluation on Jul 31, 2023 Published on Jun 15, 2023
  • Identifying SARS-CoV-2 entry inhibitors through drug repurposing screens of SARS-S and MERS-S pseudotyped particles

    This article's authors
    1. Catherine Z. Chen
    2. Miao Xu
    3. Manisha Pradhan
    4. Kirill Gorshkov
    5. Jennifer Petersen
    6. Marco R. Straus
    7. Wei Zhu
    8. Paul Shinn
    9. Hui Guo
    10. Min Shen
    11. Carleen Klumpp-Thomas
    12. Samuel G. Michael
    13. Joshua Zimmerberg
    14. Wei Zheng
    15. Gary R. Whittaker
    This article has 1 evaluations Latest evaluation on Jul 12, 2020 Published on Aug 18, 2020
  • A Strategy to Treat COVID-19 Disease with Targeted Delivery of Inhalable Liposomal Hydroxychloroquine: A Non-clinical Pharmacokinetic Study

    This article's authors
    1. Tien-Tzu Tai
    2. Tzung-Ju Wu
    3. Huey-Dong Wu
    4. Yi-Chen Tsai
    5. Hui-Ting Wang
    6. An-Min Wang
    7. Sheue-Fang Shih
    8. Yee-Chun Chen
    This article has 1 evaluations Latest evaluation on Jul 11, 2020 Published on Jul 10, 2020
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