Cancer Biology
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Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma
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FAK modulates glioblastoma stem cell energetics via regulation of glycolysis and glutamine oxidation
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Control of mitochondrial dynamics by dPGC1 limits Yorkie-induced oncogenic growth in Drosophila
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Acquired resistance to sotorasib in KRASG12Cmutant NSCLC is vulnerable to PI3K-mTOR pathway inhibition mediated by 4E-BP1 regulator of cap-dependent translation
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Potent synthetic lethality between PLK1 and EYA-family inhibitors in tumours of the central and peripheral nervous system
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Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis
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Telomeres control human telomerase ( hTERT ) expression through non-telomeric TRF2
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Capillary constrictions prime cancer cell tumorigenicity through PIEZO1
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Reconfiguration of tumor cells with LCOR transcription factor mRNA nanotherapy to enhance immunotherapy efficacy
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Sex differences in bile acid homeostasis and excretion underlie the disparity in liver cancer incidence between males and females
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