Biochemistry
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The Structural Dynamics of IRE1 and its Interaction with Unfolded Peptides
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Occupancy of the HbYX hydrophobic pocket is sufficient to induce gate opening in the archaeal 20S proteasomes
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Structural insights into heterohexameric assembly of epilepsy-related ligand–receptor complex LGI1–ADAM22
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A novel broad-spectrum antibiotic targets multiple-drug-resistant bacteria with dual binding targets and no detectable resistance
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Gut Microbe-Derived Trimethylamine Shapes Circadian Rhythms Through the Host Receptor TAAR5
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RamanMAE: Masked Autoencoders Enable Efficient Molecular Imaging by Learning Biologically Meaningful Spectral Representations
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Membrane curvature regulates Ups1 dependent phosphatidic acid transfer across lipid bilayers
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Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
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Elevated Ubiquitin Phosphorylation by PINK1 Contributes to Proteasomal Impairment and Promotes Neurodegeneration
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Dual-specific autophosphorylation of kinase IKK2 enables phosphorylation of substrate IκBα through a phosphoenzyme intermediate
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