The Paradox of Pressure: A Case of Ceftriaxone-Induced Hypertensive Anaphylaxis Where Collapse Meets Surge – A Case Report

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Abstract

Anaphylaxis is a potentially life-threatening hypersensitivity reaction, most commonly associated with beta-lactam antibiotics. Although hypotension is a hallmark clinical feature, paradoxical presentations such as hypertensive responses have been documented. We report a case of a 40-year-old male who developed severe respiratory distress and hypertensive anaphylaxis following intravenous administration of ceftriaxone. The case emphasizes the need for clinical vigilance and timely intervention even in atypical anaphylactic presentations.

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