Knowledge, Attitudes, and Practices Towards Sickle Cell Anaemia Among Healthcare Professionals in Cabinda Province, Angola

Background: Sickle cell anaemia (SCA) is a serious global public health problem, with a high geographical distribution of burden that negatively affects quality of life. Aim: To evaluate the Knowledge, Attitudes, and Practices (KAP) towards SCA condition and care among healthcare professionals (HCPs).Setting: This study was conducted in Cabinda, an exclave and province of Angola. Methods: This convergent mixed methods study integrated quantitative and qualitative data. A self-administered cross-sectional survey (n=500) was the primary instrument. Quantitative data were analysed using descriptive and inferential statistics while qualitative responses underwent thematic analysis to reveal patterns and contextual factors.Results: A total of 293 responses were returned (response rate 59%). Fifty-two (18%) respondents were male and 241 (82%) were female. Using a common scoring method, the overall mean scores for KAP were 14.79 ± 4.95 (out of a maximum score of 27), 2.73 ± 1.40 (maximum 6), and 3.00 ± 1.68 (maximum 5), respectively. Most respondents (98%) knew about SCA primarily through professional training (47%). Overall, quantitative findings revealed gaps in knowledge, particularly in pain management and genetic counselling. Qualitative insights indicated that personal experiences and institutional support influenced HCP attitudes. Nevertheless, all respondents stated they would support the establishment of a standalone clinic for SCA patients. Conclusion: Although HCPs demonstrated high awareness of SCA, their detailed knowledge of the condition remained limited. Contribution: This study provides valuable insights into SCA prevention and management among HCPs in Cabinda province and underscores the necessity for a holistic approach to enhance SCA care delivery.